An ex vivo Study of Foam Cell Formation and Cholesterol Clearance in Macrophages Isolated from Patients with Hypertriglyceridemia and Low High-Density Lipoprotein Cholesterol Treated with High-Dose Simvastatin

  • Annabelle Rodriguez Rita Fishelevich
  • Published 2000
High-density lipoproteins (HDL) are thought to be cardioprotective due to their role in decreasing cholesterol accumulation and in enhancing cholesterol removal from foam cells. Our study will examine foam cell formation and HDL-mediated cholesterol removal from macrophages isolated from patients with hypertriglyceridemia and low HDL. Peripheral blood… (More)