An evolutionary view of human recombination

  title={An evolutionary view of human recombination},
  author={Graham M Coop and Molly Przeworski},
  journal={Nature Reviews Genetics},
Recombination has essential functions in mammalian meiosis, which impose several constraints on the recombination process. However, recent studies have shown that, in spite of these roles, recombination rates vary tremendously among humans, and show marked differences between humans and closely related species. These findings provide important insights into the determinants of recombination rates and raise new questions about the selective pressures that affect recombination over different… CONTINUE READING
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