An evolutionary strategy for a stealthy intracellular Brucella pathogen.

  title={An evolutionary strategy for a stealthy intracellular Brucella pathogen.},
  author={Anna Martirosyan and Edgardo Moreno and Jean-Pierre E. Gorvel},
  journal={Immunological reviews},
  volume={240 1},
Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals and leads to a debilitating febrile illness that can progress into a long lasting disease with severe complications in humans. Its virulence depends on survival and replication properties in host cells. In this review, we describe the stealthy strategy used by Brucella to escape recognition of the innate immunity and the means by which this bacterium evades intracellular destruction. We also discuss… CONTINUE READING


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