An evolutionary scenario for one of the largest yeast gene families.

  title={An evolutionary scenario for one of the largest yeast gene families.},
  author={Laurence Despons and B{\'e}n{\'e}dicte Wirth and V{\'e}ronique Leh Louis and Serge Potier and Jean-Luc Souciet},
  journal={Trends in genetics : TIG},
  volume={22 1},
The DUP gene family of Saccharomyces cerevisiae comprises 23 members that can be divided into two subfamilies--DUP240 and DUP380. The location of the DUP loci suggests that at least three mechanisms were responsible for their genomic dispersion: nonreciprocal translocation at chromosomal ends, tandem duplication and Ty-associated duplication. The data we present here suggest that these nonessential genes encode proteins that facilitate membrane trafficking processes. Dup240 proteins have three… CONTINUE READING

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