An evolutionary perspective on signaling peptides: toxic peptides are selected to provide information regarding the processing of the propeptide, which represents the phenotypic state of the signaling cell

@inproceedings{Harris2015AnEP,
  title={An evolutionary perspective on signaling peptides: toxic peptides are selected to provide information regarding the processing of the propeptide, which represents the phenotypic state of the signaling cell},
  author={Keith Daniel Harris and Ari Barzilai and Amotz Zahavi and David Granot and Uzi Motro},
  booktitle={F1000Research},
  year={2015}
}
Structurally similar short peptides often serve as signals in diverse signaling systems. Similar peptides affect diverse physiological pathways in different species or even within the same organism. Assuming that signals provide information, and that this information is tested by the structure of the signal, it is curious that highly similar signaling… CONTINUE READING