• DOI:10.1038/nrc.2017.102
Corpus ID: 19077232

An evolutionary perspective on field cancerization

@article{Curtius2018AnEP,
  title={An evolutionary perspective on field cancerization},
  author={K. Curtius and N. A. Wright and T. Graham},
  journal={Nature Reviews Cancer},
  year={2018},
  volume={18},
  pages={19-32}
}

K. Curtius, N. A. Wright, T. Graham

Published 2018

Medicine, Biology

Nature Reviews Cancer

Tumorigenesis begins long before the growth of a clinically detectable lesion and, indeed, even before any of the usual morphological correlates of pre-malignancy are recognizable. Field cancerization, which is the replacement of the normal cell population by a cancer-primed cell population that may show no morphological change, is now recognized to underlie the development of many types of cancer, including the common carcinomas of the lung, colon, skin, prostate and bladder. Field… CONTINUE READING

View on Nature

qmro.qmul.ac.uk

Save to Library

Create Alert

Cite

Launch Research Feed