An evaluation of voclosporin for the treatment of lupus nephritis
@article{Sin2018AnEO, title={An evaluation of voclosporin for the treatment of lupus nephritis}, author={Fang En Sin and David A. Isenberg}, journal={Expert Opinion on Pharmacotherapy}, year={2018}, volume={19}, pages={1613 - 1621} }
ABSTRACT Introduction: Lupus nephritis (LN) is associated with significant morbidity and mortality. Current treatment outcomes remain suboptimal. No disease modifying medications are licensed for the treatment of LN. Voclosporin, a novel calcineurin inhibitor, has been investigated as induction therapy in LN in combination with myocophenolate mofetil (MMF) and a glucocorticoid (GC). Two phase II trials of voclosporin were the first trials of a potential treatment of active LN that met their…
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