An evaluation of the locomotor stimulating action of ethanol in rats and mice

@article{Frye1981AnEO,
  title={An evaluation of the locomotor stimulating action of ethanol in rats and mice},
  author={Gerald D. Frye and George R. Breese},
  journal={Psychopharmacology},
  year={1981},
  volume={75},
  pages={372-379}
}
The locomotor activity of groups of three CD-1 female mice was increased by 1.0 and 2.0 g/kg ethanol, IP, was decreased during the first hour and increased during the second hour by 3.0 and 4.0 g/kg, and was decreased by 5.0 g/kg. The dose (2.0 g/kg) that caused the greatest increase in locomotor activity did not impair motor coordination, measured by the height of aerial righting in mice. Tests after oral administration of ethanol showed that the increase in locomotor activity of mice was not… CONTINUE READING
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Similarities in the central actions of GABAmimetic drugs and ethanol

  • G Frye, G Breese, R Mailman, R Vogel, R Mueller
  • Brain Res Bull
  • 1979

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