An evaluation of the Mitchell hypothesis of chemiosmotic coupling in oxidative and photosynthetic phosphorylation.

@article{Slater1967AnEO,
  title={An evaluation of the Mitchell hypothesis of chemiosmotic coupling in oxidative and photosynthetic phosphorylation.},
  author={E. C. Slater},
  journal={European journal of biochemistry},
  year={1967},
  volume={1 3},
  pages={
          317-26
        }
}
  • E. C. Slater
  • Published 1967
  • Medicine, Chemistry
  • European journal of biochemistry
The Mitchell hypothesis of chemiosmotic coupling in oxidative phosphorylation is examined in the light of experimental data on oxidative phosphorylation at present available. The following objections are brought against the theory: 1. Data on the magnitude of the phosphate potential against which ATP can be synthesized by the respiratory chain require, on the basis of chemiosmotic coupling, very effective proton and/or cation extrusion and/or anion uptake by the mitochondria. Experimental… Expand
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  • Chemistry, Medicine
  • Journal of theoretical biology
  • 1970
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  • 1975
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The effect of various energy-conversion states of chloroplasts on proton and electron transport.
  • R. Dilley
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
  • 1970
TLDR
In this scheme, energy-transfer inhibition or the absence of the complete coupling system would lead to greater H+ ion transport activity due to the alternative use of the highenergy state by the ion-transport mechanism; (B) the proton-trans transport carrier could be linked to one of two electron transport chains. Expand
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TLDR
The end result of the coupling between the flows through the o/r and h/d pathways in oxidative phosphorylation in mitochondria is that, for the equivalent of each pair of electrons traversing the respiratory chain, up to 3 anhydro-bond equivalents may normally traverse the h/D pathway from adenosine diphosphate plus inorganic phosphate (ADP +Pi) to water. Expand
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Abstract 1. 1. Evidence is presented showing that the burst in ATP synthesis, occuring on addition of ADp to rat-liver mitochondria supplemented with β-hydroxybutyrate and phosphate, is due to theExpand
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It is shown that an acid-base transition, performed in the manner described by Jagendorf and Uribe, causes spinach chloroplasts to emit a flash of light having the spectrum of chlorophyll fluorescence, and the dependence of this chemiluminescence on a variety of conditions will be described. Expand
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From a consideration of the treatment of the functions of chains of catalysts ( Williams, 1961a ) a tentative scheme for oxidative phosphorylation is suggested. Evidence for each of the steps in theExpand
Simple Allosteric Model for Membrane Pumps
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It appears timely to point out that transport contingent on a chemical reaction can be understood in terms of a very simple molecular model, for which a noteworthy precedent can be found among recent crystal structure determinations. Expand
Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism
Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism
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