An evaluation of different Cripto-1 antibodies and their variable results.

@article{Gudbergsson2019AnEO,
  title={An evaluation of different Cripto-1 antibodies and their variable results.},
  author={Johann Mar Gudbergsson and Meg Duroux},
  journal={Journal of cellular biochemistry},
  year={2019}
}
Cripto-1 is a protein expressed during embryonal development and has been linked to several malignant processes in cancer. Since the discovery of cripto-1 in the late 1980s, it has become a subject of biomarker investigation in several types of cancer which in many cases relies on immunolocalization of cripto-1 using antibodies. Investigating cripto-1 expression and localization in primary glioblastoma cells, we discovered nonspecific binding of cripto-1 antibody to the extracellular matrix… CONTINUE READING