An evaluation of dapsone gel 5% in the treatment of acne vulgaris

  title={An evaluation of dapsone gel 5% in the treatment of acne vulgaris},
  author={A. Pickert and S. Raimer},
  journal={Expert Opinion on Pharmacotherapy},
  pages={1515 - 1521}
  • A. Pickert, S. Raimer
  • Published 2009
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • Background: Oral dapsone has been available for over 60 years. Its first clinical use was discovered in 1945, when it was found to be efficacious in inhibiting the progression of leprosy. The combined antibacterial and anti-inflammatory pharmacologic activities of dapsone have made it a widely investigated drug, particularly for use in refractory and unusual dermatologic conditions. However, the possibility of significant hematological side effects, even at low doses, has limited its use… CONTINUE READING
    26 Citations
    Update on the use of dapsone in dermatology
    • 3
    Newer Approaches to the Treatment of Acne Vulgaris
    • T. Simonart
    • Medicine
    • American Journal of Clinical Dermatology
    • 2012
    • 42
    • PDF
    Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone
    • 8
    Topical acne treatments in Europe and the issue of antimicrobial resistance
    • 37


    Pharmacokinetics of Dapsone Gel, 5% for the Treatment of Acne Vulgaris
    • 29
    • Highly Influential
    Dapsone gel 5% for the treatment of acne vulgaris: safety and efficacy of long-term (1 year) treatment.
    • 54
    Hematologic safety of dapsone gel, 5%, for topical treatment of acne vulgaris.
    • 49
    • PDF
    Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris.
    • 96
    Dapsone: modes of action, toxicity and possible strategies for increasing patient tolerance
    • M. Coleman
    • Medicine
    • The British journal of dermatology
    • 1993
    • 187
    Management of acne: a report from a Global Alliance to Improve Outcomes in Acne.
    • 734
    Efficacy and safety of dapsone gel 5% for the treatment of acne vulgaris in adolescents.
    • 21
    • PDF
    A comparison of dapsone with 13‐cis retinoic acid in the treatment of nodular cystic acne
    • 34
    Dapsone-induced hemolytic anemia.
    • 52