An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol.

@article{Jiang1992AnER,
  title={An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol.},
  author={Shu Ye Jiang and Douglas M. Wolf and Jonathan M. Yingling and Chawnshang Chang and V. Craig Jordan},
  journal={Molecular and cellular endocrinology},
  year={1992},
  volume={90 1},
  pages={77-86}
}
The antiestrogen tamoxifen has been successfully used to control estrogen receptor (ER) and progesterone receptor positive breast cancer. However, the development of antiestrogen resistance is frequently observed in patients following long term treatment. We have studied the development of antiestrogen resistance in vitro and established an antiestrogen… CONTINUE READING