An estrogen-dependent esterase activity in MCF-7 cells.

@article{Katz1987AnEE,
  title={An estrogen-dependent esterase activity in MCF-7 cells.},
  author={J. Katz and T. Finlay and S. Banerjee and M. Levitz},
  journal={Journal of steroid biochemistry},
  year={1987},
  volume={26 6},
  pages={
          687-92
        }
}
The presence of steroidal esters in hormonally sensitive tissues lends importance to the esterases which convert the biologically inactive adducts to the parent potent forms. Accordingly, esterase-activities were studied in a human breast cancer model--the MCF-7 cell line. Tritiated estradiol esters- estradiol-17-acetate (EA), estradiol-17-valerate (EV) and estradiol-17-stearate (ES) were tested systematically, but 3 beta-ol esters of androgens, and phorbol diesters were also investigated. All… Expand
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References

SHOWING 1-10 OF 25 REFERENCES
The naturally occurring C-17 fatty acid esters of estradiol are long-acting estrogens.
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
Radiochemical evidence for estradiol-17-fatty acid esters in human blood.
...
1
2
3
...