An estimation of the number of cells in the human body

@article{Bianconi2013AnEO,
  title={An estimation of the number of cells in the human body},
  author={Eva Bianconi and Allison Piovesan and Federica Facchin and Alina Beraudi and Raffaella Casadei and Flavia Frabetti and Lorenza Vitale and Maria Chiara Pelleri and Simone Tassani and Francesco Piva and Soledad P{\'e}rez-Amodio and Pierluigi Strippoli and Silvia Canaider},
  journal={Annals of Human Biology},
  year={2013},
  volume={40},
  pages={463 - 471}
}
BACKGROUND All living organisms are made of individual and identifiable cells, whose number, together with their size and type, ultimately defines the structure and functions of an organism. [] Key MethodRESULTS A current estimation of human total cell number calculated for a variety of organs and cell types is presented. These partial data correspond to a total number of 3.72 × 10(13). CONCLUSIONS Knowing the total cell number of the human body as well as of individual organs is important from a cultural…
View on Taylor & Francis
tandfonline.com
828 Citations
Highly Influential Citations
39
Background Citations
292
Methods Citations
15
Results Citations
4

828 Citations

Revised Estimates for the Number of Human and Bacteria Cells in the Body

This analysis updates the widely-cited 10:1 ratio, showing that the number of bacteria in the authors' bodies is actually of the same order as thenumber of human cells.

Different Cells of the Human Body: Categories and Morphological Characters

This review shed a light on these cell categories and their morphologies, where stem cell category is the cells responsible for the regeneration of damaged or lost cells, whereas protein-secreting cells are thoseresponsible for the production and secretion of proteins.

How Low Can You Go? The Numbers of Cells That Make Up Bodies: Large Numbers and Small Numbers

Through a conversation between parents and their child at the dinner table, this book will think about how many or how few cells are in various organisms by comparing their numbers to grains of rice in a bowl.

Dynamics of cell mass and size control in multicellular systems and the human body

A mathematical model for cell mass fluctuations is provided and it is demonstrated that the proposed model leads to shifts of mass between the intracellular and extracellular fluid compartments in the human body that are approximately or smaller than 0.25 mg and, therefore, perfectly viable.

The distribution of cellular turnover in the human body

A comprehensive census of the dynamics of death and regeneration of cells and tissues provides an estimation of the distribution of cellular turnover in the human body.

The distribution of cellular turnover in the human body

A comprehensive census of the dynamics of death and regeneration of cells and tissues provides an estimation of the distribution of cellular turnover in the human body.

Mechanistic aspects of mammalian cell size control

Several lines of evidence indicate that the product of this gene, which is called “Largen”, regulates mRNA translation in a manner associated with the upregulation of a specific subset of mRNAs, many of which affect mitochondrial function.

Quantifying the osteocyte network in the human skeleton.

The Actual Property of; Bio-Energy, Cells Divisions and some Important Concepts of Different Creatures

It is indicated one scientific fact that DNA extraction processes that widely used for long time ago by many researchers produce unsaturated fatty acids do not produce DNA or nucleotides molecules, therefore, all theories that depended on these extractions processes are incorrect.

Reduction, proliferation, and differentiation defects of stem cells over time: a consequence of selective accumulation of old centrioles in the stem cells?

Centrioles are more subjected to destruction than other structures of a cell—which makes centrioles potentially the main structure of aging.
...

175 References

Cell number and cell characteristics of the normal human lung.

Overall mean nuclear diameters of the nuclei of 5 major cell types in the lung parenchyma were found to have little variation, and proportions of cells in the alveolar region and their average thickness, size, and surface areas were relatively constant.

Allometric relationships of cell numbers and size in the mammalian lung.

The lung is unique among organs in the diversity and function of individual cell types, such as mechanical, sensory, secretory, transporting, and circulating cells, making it an ideal organ for examining the varieties in cell characteristics across different species.

Cell number in human heart in atrophy, hypertrophy, and under the influence of cytostatics.

  • C. AdlerU. Costabel
  • Medicine, Biology
    Recent advances in studies on cardiac structure and metabolism
  • 1975
The DNA content was determined in 30 human hearts from different age groups and of different weight classes and revealed that polyploidisation is caused by chronic hyperfunction of the heart.

Cell number and distribution in human and rat airways.

Airway surface area from trachea to bronchioles was 2,471 +/- 320 and 27.2 +/- 1.7 cm2 in human and rat lungs, respectively, less than half of the estimates based on current lung models.

[How to reach the right size?].

A better understanding of how secreted factors regulate size will hopefully allow us to develop new therapeutic procedures to treat birth defects or diseases that affect tissue size.

The Cell: A Molecular Approach

  • Sreeurpa Ray
  • Biology
    The Yale Journal of Biology and Medicine
  • 2014
The Cell: A Molecular Approach is a helpful resource for understanding the basic science of cellular and molecular biology and is a good read for students just beginning to study the complexities of biology, as a good review for intermediate students who already have an understanding of the subject.

Studies of human adipose tissue. Adipose cell size and number in nonobese and obese patients.

There are two distinct periods early in life during which hypercellularity of the adipose tissue are most likely to occur: very early within the first few years, and again from age 9 to 13 yr, which indicate that the total adipose number of an individual is best and most practically estimated by division of total body fat by the mean of the fat sizes of at least three subcutaneous sites.

Glomerular cell number in normal subjects and in type 1 diabetic patients.

The essentially constant glomerular cell density in nondiabetic and diabetic subjects under different circumstances possibly indicates an underlying propensity for the glomerulus to regulate its architecture to maintain a constant number of cells per volume, no matter the size of the glomersulus or the severity of diabetic nephropathy studied in this set of patients.

Controlling the size of organs and organisms.

The control of neuron number.

In comparing strategies used to control neuron number, it is useful to view nervous system development as occurring in three phases, where each is a process, not an event.
...