An estimation of the number of cells in the human body

@article{Bianconi2013AnEO,
  title={An estimation of the number of cells in the human body},
  author={Eva Bianconi and Allison Piovesan and Federica Facchin and Alina Beraudi and Raffaella Casadei and Flavia Frabetti and Lorenza Vitale and Maria Chiara Pelleri and Simone Tassani and Francesco Piva and Soledad P{\'e}rez-Amodio and Pierluigi Strippoli and Silvia Canaider},
  journal={Annals of Human Biology},
  year={2013},
  volume={40},
  pages={463 - 471}
}
BACKGROUND All living organisms are made of individual and identifiable cells, whose number, together with their size and type, ultimately defines the structure and functions of an organism. [] Key MethodRESULTS A current estimation of human total cell number calculated for a variety of organs and cell types is presented. These partial data correspond to a total number of 3.72 × 10(13). CONCLUSIONS Knowing the total cell number of the human body as well as of individual organs is important from a cultural…
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References

SHOWING 1-10 OF 175 REFERENCES
Cell number and cell characteristics of the normal human lung.
TLDR
Overall mean nuclear diameters of the nuclei of 5 major cell types in the lung parenchyma were found to have little variation, and proportions of cells in the alveolar region and their average thickness, size, and surface areas were relatively constant.
Allometric relationships of cell numbers and size in the mammalian lung.
TLDR
The lung is unique among organs in the diversity and function of individual cell types, such as mechanical, sensory, secretory, transporting, and circulating cells, making it an ideal organ for examining the varieties in cell characteristics across different species.
Cell number in human heart in atrophy, hypertrophy, and under the influence of cytostatics.
  • C. Adler, U. Costabel
  • Medicine, Biology
    Recent advances in studies on cardiac structure and metabolism
  • 1975
TLDR
The DNA content was determined in 30 human hearts from different age groups and of different weight classes and revealed that polyploidisation is caused by chronic hyperfunction of the heart.
Cell number and distribution in human and rat airways.
TLDR
Airway surface area from trachea to bronchioles was 2,471 +/- 320 and 27.2 +/- 1.7 cm2 in human and rat lungs, respectively, less than half of the estimates based on current lung models.
The Cell: A Molecular Approach
  • Sreeurpa Ray
  • Biology
    The Yale Journal of Biology and Medicine
  • 2014
TLDR
The Cell: A Molecular Approach is a helpful resource for understanding the basic science of cellular and molecular biology and is a good read for students just beginning to study the complexities of biology, as a good review for intermediate students who already have an understanding of the subject.
Studies of human adipose tissue. Adipose cell size and number in nonobese and obese patients.
TLDR
There are two distinct periods early in life during which hypercellularity of the adipose tissue are most likely to occur: very early within the first few years, and again from age 9 to 13 yr, which indicate that the total adipose number of an individual is best and most practically estimated by division of total body fat by the mean of the fat sizes of at least three subcutaneous sites.
Glomerular cell number in normal subjects and in type 1 diabetic patients.
TLDR
The essentially constant glomerular cell density in nondiabetic and diabetic subjects under different circumstances possibly indicates an underlying propensity for the glomerulus to regulate its architecture to maintain a constant number of cells per volume, no matter the size of the glomersulus or the severity of diabetic nephropathy studied in this set of patients.
Controlling the size of organs and organisms.
The control of neuron number.
TLDR
In comparing strategies used to control neuron number, it is useful to view nervous system development as occurring in three phases, where each is a process, not an event.
Organ scaling in mammals: the liver.
  • J. Prothero
  • Biology, Environmental Science
    Comparative biochemistry and physiology. A, Comparative physiology
  • 1982
...
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