An estimate of the heritable fraction of childhood cancer.

@article{Narod1991AnEO,
  title={An estimate of the heritable fraction of childhood cancer.},
  author={S. A. Narod and Christoph Stiller and Gilbert M. Lenoir},
  journal={British Journal of Cancer},
  year={1991},
  volume={63},
  pages={993 - 999}
}
We have reviewed the records of the 16,564 cases of childhood cancer diagnosed from 1971 to 1983 which were reported to the National Registry of Childhood Tumours in Great Britain for the presence of underlying genetic disease in order to estimate the proportion which results from inherited mutations. A genetic condition was listed for 509 patients, or 3.07% of the total number of tumours. The most frequently recorded diagnoses were: bilateral retinoblastoma (162 cases); Down syndrome (135… CONTINUE READING

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