An essential role for interleukin-5 and eosinophils in helminth-induced airway hyperresponsiveness.

Abstract

Infection with the parasitic helminth Brugia malayi can result in development of a severe asthmatic response termed tropical pulmonary eosinophilia. This disease, thought to result from a host inflammatory response to blood parasites which become trapped in the lung microvasculature, is characterized by a profound eosinophilic infiltration into the lungs… (More)

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