An ergot alkaloid biosynthesis gene and clustered hypothetical genes from Aspergillus fumigatus.

@article{Coyle2005AnEA,
  title={An ergot alkaloid biosynthesis gene and clustered hypothetical genes from Aspergillus fumigatus.},
  author={Christine M. Coyle and Daniel G Panaccione},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 6},
  pages={
          3112-8
        }
}
The ergot alkaloids are a family of indole-derived mycotoxins with a variety of significant biological activities. Aspergillus fumigatus, a common airborne fungus and opportunistic human pathogen, and several fungi in the relatively distant taxon Clavicipitaceae (clavicipitaceous fungi) produce different sets of ergot alkaloids. The ergot alkaloids of these divergent fungi share a four-member ergoline ring but differ in the number, type, and position of the side chains. Several genes required… CONTINUE READING

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