An epithelial niche in the Drosophila ovary undergoes long-range stem cell replacement.

@article{Nystul2007AnEN,
  title={An epithelial niche in the Drosophila ovary undergoes long-range stem cell replacement.},
  author={Todd G Nystul and Allan C Spradling},
  journal={Cell stem cell},
  year={2007},
  volume={1 3},
  pages={277-85}
}
Adult epithelial stem cells are thought to reside in specific niches, where they are maintained by adhesion to stromal cells and by intercellular signals. In niches that harbor multiple adjacent stem cells, such as those maintaining Drosophila germ cells, lost stem cells are replaced by division of neighboring stem cells or reversion of transit cells. We have characterized the Drosophila follicle stem cell (FSC) niche as a model of the epithelial niche to learn whether nonneighboring cells can… CONTINUE READING