An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants.

@article{Vigan2014AnEP,
  title={An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants.},
  author={Maria Alessandra Vigan{\`o} and Robert Ivanek and Piotr J. Balwierz and Philipp Berninger and Erik van Nimwegen and Klaus Karjalainen and Antonius G. Rolink},
  journal={European journal of immunology},
  year={2014},
  volume={44 4},
  pages={1181-93}
}
Cellular differentiation of the T-cell branch of the immune system begins with the HSC, which undergoes a series of stages characterized by progressive restriction in multipotency and acquisition of specific lineage identity At the molecular level, the restriction of cell potential, commitment, and differentiation to a specific lineage is achieved through… CONTINUE READING