An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

  title={An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease},
  author={Steve Horvath and Michael Gurven and Morgan E. Levine and Benjamin C Trumble and Hillard S. Kaplan and Hooman Allayee and Beate R. Ritz and Brian H Chen and Ake Lu and Tammy M. Rickabaugh and Beth D. Jamieson and Dianjianyi Sun and Shengxu Li and Wei Chen and Llu{\'i}s Quintana-Murci and Maud Fagny and Michael S. Kobor and Philip S. Tsao and Alex P. Reiner and Kerstin L. Edlefsen and Devin M Absher and Themistocles L. Assimes},
  booktitle={Genome Biology},
Epigenetic biomarkers of aging (the “epigenetic clock”) have the potential to address puzzling findings surrounding mortality rates and incidence of cardio-metabolic disease such as: (1) women consistently exhibiting lower mortality than men despite having higher levels of morbidity; (2) racial/ethnic groups having different mortality rates even after adjusting for socioeconomic differences; (3) the black/white mortality cross-over effect in late adulthood; and (4) Hispanics in the United… CONTINUE READING


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