An epidemiologic study to determine the prevalence of the HLA-B*5701 allele among HIV-positive patients in Europe.

@article{Orkin2010AnES,
  title={An epidemiologic study to determine the prevalence of the HLA-B*5701 allele among HIV-positive patients in Europe.},
  author={Chloe M. Orkin and Jianmin Wang and Colm Bergin and Jean-Michel Molina and Adriano Lazzarin and Matthias Cavassini and Stefan Esser and Juan-Luis G{\'o}mez Sirvent and Helen C Pearce},
  journal={Pharmacogenetics and genomics},
  year={2010},
  volume={20 5},
  pages={307-14}
}
OBJECTIVES HLA-B*5701 is a major histocompatibility complex class I allele associated with an immunologically-mediated hypersensitivity reaction to abacavir. The objectives of this study were to evaluate HLA-B*5701 prevalence among European, HIV-1-infected patients and to compare the local and central laboratory screening results. METHODS Data were combined from six multicentre, prospective studies involving 10 European countries in which HIV-1-infected patients (irrespective of treatment… CONTINUE READING
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