An epidemiologic study of index and family infectious mononucleosis and adult Hodgkin's disease (HD): evidence for a specific association with EBV+ve HD in young adults.

@article{Alexander2003AnES,
  title={An epidemiologic study of index and family infectious mononucleosis and adult Hodgkin's disease (HD): evidence for a specific association with EBV+ve HD in young adults.},
  author={Freda E. Alexander and Davia J Lawrence and June Freeland and Andrew Stephen Krajewski and Brian J. Angus and Graham Malcolm Taylor and Ruth F. Jarrett},
  journal={International journal of cancer},
  year={2003},
  volume={107 2},
  pages={
          298-302
        }
}
Infectious mononucleosis (IM) is an established risk factor for Hodgkin's disease (HD). A substantial minority (33%) of cases of HD have Epstein-Barr virus (EBV) DNA within the malignant cells (are EBV+ve). It is unclear whether risk after IM applies specifically to EBV+ve HD. We report the results of a population-based case-control study of HD in adults (n = 408 cases of classical HD, 513 controls) aged 16-74 years; the case series included 113 EBV+ve and 243 EBV+ve HD. Analyses compared total… CONTINUE READING
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