An epidemiologic approach to ecogenetics.

  title={An epidemiologic approach to ecogenetics.},
  author={Muin J. Khoury and Michael J Adams and W. Dana Flanders},
  journal={American journal of human genetics},
  volume={42 1},
Although "ecogenetics" seeks to examine genetically mediated differences in susceptibility to environmental agents, researchers often examine the relation between genetic markers and disease without regard to environmental determinants. By using epidemiologic definitions of genotype-environment interaction, it can be shown that the relative risk of disease for the genetic marker is a function of the frequency of exposure to the environmental agent, the strength of interaction between the… CONTINUE READING