An enzyme-immunoassay for estriol.


A practical method was developed for enzyme-immunoassay of serum estriol, with alkaline-phosphatase as a marker enzyme. Alkaline-phosphatase was conjugated with estriol-6-(O-carboxymethyl) oxime using water soluble carbodiimide. The estriol-alkaline-phosphatase complex, which has both enzyme activity and capacity to bind anti-estriol serum, was obtained by… (More)


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@article{Otsuki1979AnEF, title={An enzyme-immunoassay for estriol.}, author={Yoshio Otsuki and Kozo Yamaji and Osamu Tanizawa and Masatoshi Fujita and K Kurachi and Kenichi Ishibashi and Kiyoshi Miyai}, journal={Endocrinologia japonica}, year={1979}, volume={26 6}, pages={687-91} }