An enriched environment improves cognitive performance after early-life status epilepticus accompanied by an increase in phosphorylation of extracellular signal-regulated kinase 2.

@article{Wang2007AnEE,
  title={An enriched environment improves cognitive performance after early-life status epilepticus accompanied by an increase in phosphorylation of extracellular signal-regulated kinase 2.},
  author={Chien-An Wang and Ming-Chi Lai and Chun-Chung Lui and San-Nan Yang and M M Tiao and Chih-Sung Hsieh and Hung-Hong Lin and Li-Tung Huang},
  journal={Epilepsy & behavior : E&B},
  year={2007},
  volume={11 3},
  pages={303-9}
}
An enriched environment can enhance brain recovery in animals with early-life status epilepticus (SE). The purpose of this study was to determine the effects of early-life SE on spatial memory and hippocampal extracellular signal-regulated kinase (ERK) level, and the possible therapeutic effects of the enriched environment. Rats were assigned randomly to four groups: (1) control rats (nonenriched control); (2) control rats housed in an enriched environment from Postnatal Day (P) 25 to P40… CONTINUE READING

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