An enlarged largest subunit of Plasmodium falciparum RNA polymerase II defines conserved and variable RNA polymerase domains.

@article{Li1989AnEL,
  title={An enlarged largest subunit of Plasmodium falciparum RNA polymerase II defines conserved and variable RNA polymerase domains.},
  author={W. B. Li and D. Bzik and H. Gu and M. Tanaka and B. A. Fox and J. Inselburg},
  journal={Nucleic acids research},
  year={1989},
  volume={17 23},
  pages={
          9621-36
        }
}
We have isolated the gene encoding the largest subunit of RNA polymerase II from Plasmodium falciparum. The RPII gene is expressed in the asexual erythrocytic stages of the parasite as a 9 kb mRNA, and is present as a single copy gene located on chromosome 3. The P. falciparum RPII subunit is the largest (2452 amino acids) eukaryotic RPII subunit, and it contains enlarged variable regions that clearly separate and define five conserved regions of the eukaryotic RPII largest subunits. A… Expand
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