An enantioselective synthesis of (+)-(S)-[n]-gingerols via the L-proline-catalyzed aldol reaction.

@article{Ma2009AnES,
  title={An enantioselective synthesis of (+)-(S)-[n]-gingerols via the L-proline-catalyzed aldol reaction.},
  author={Shichao Ma and Shilei Zhang and Wenhu Duan and Wei Wang},
  journal={Bioorganic & medicinal chemistry letters},
  year={2009},
  volume={19 14},
  pages={3909-11}
}
An enantioselective approach to (+)-(S)-[n]-gingerols (1a-c) has been developed. The requisite stereogenic centers of target molecules are facilely constructed by the proline-catalyzed cross-aldol reaction from readily available achiral starting materials. 

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