An electrospun polydioxanone patch for the localisation of biological therapies during tendon repair.

@article{Hakimi2012AnEP,
  title={An electrospun polydioxanone patch for the localisation of biological therapies during tendon repair.},
  author={Osnat Hakimi and Rita Murphy and Urszula Stachewicz and Stephen Hislop and Alun J. Carr},
  journal={European cells & materials},
  year={2012},
  volume={24},
  pages={344-57; discussion 357}
}
Rotator cuff tendon pathology is thought to account for 30-70 % of all shoulder pain. For cases that have failed conservative treatment, surgical re-attachment of the tendon to the bone with a non-absorbable suture is a common option. However, the failure rate of these repairs is high, estimated at up to 75 %. Studies have shown that in late disease stages the tendon itself is extremely degenerate, with reduced cell numbers and poor matrix organisation. Thus, it has been suggested that adding… CONTINUE READING
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Electrospun matrices for localized drug delivery: current technologies and selected biomedical applications.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V • 2012

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