An electron microscopical study of chronic ulcers of the colon in rats.

@article{Reeve1977AnEM,
  title={An electron microscopical study of chronic ulcers of the colon in rats.},
  author={Dr. D. R. E. Reeve},
  journal={British journal of experimental pathology},
  year={1977},
  volume={58 1},
  pages={63-77}
}
Chronic colonic ulcers in the rat were produced by the administration of a hydrogen peroxide enema. Lesions of up to 10 months' duration were obtained by this method and a selection was examined ultrastructurally. It was hoped that the study would reveal causes for the chronicity of the lesions. From previous work it appeared that there was no failure of… CONTINUE READING