An electron microscopic analysis of notochordal and mesenchymal cell abnormalities in embryos of Danforth's short-tail (Sd) mice.

@article{Wilson1982AnEM,
  title={An electron microscopic analysis of notochordal and mesenchymal cell abnormalities in embryos of Danforth's short-tail (Sd) mice.},
  author={Doris B. Wilson and Laurel A. Finta and Elizabeth M. Center and L G Paavola},
  journal={Virchows Archiv. B, Cell pathology including molecular pathology},
  year={1982},
  volume={39 1},
  pages={101-10}
}
Abnormalities of notochordal cells and of mesenchymal cells in embryos of Danforth's short-tail (Sd) and C57BL mice were examined by means of electron microscopy and cytochemical staining at 11.0 and 11.5 days of gestation. In abnormal (Sd/+; Sd/Sd) embryos, the notochordal cells were markedly deficient in bundles of filaments and lacked surface protrusions, and the notochordal basal lamina was continuous; in contrast, notochordal cells of normal (+/+) littermates and of C57BL embryos contained… CONTINUE READING

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