An electrochemical microprobe for detecting nitric oxide release in brain tissue.

@article{Shibuki1990AnEM,
  title={An electrochemical microprobe for detecting nitric oxide release in brain tissue.},
  author={Katsuei Shibuki},
  journal={Neuroscience research},
  year={1990},
  volume={9 1},
  pages={69-76}
}
To detect the release of nitric oxide (NO) in brain tissue, an electrochemical microprobe was developed. The output current of the probe correlated linearly with the NO concentration at the tip, and the sensitivity of the probe was between 3.5 and 106 pA per 1 microM change in NO concentration. This probe showed no sensitivity to oxygen or to oxidized derivatives of NO. The NO release from sodium nitroprusside solution was successfully detected by the probe. An NO probe inserted into the… CONTINUE READING

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