An efficient protocol to generate placental chorionic plate-derived mesenchymal stem cells with superior proliferative and immunomodulatory properties

@article{Huang2019AnEP,
  title={An efficient protocol to generate placental chorionic plate-derived mesenchymal stem cells with superior proliferative and immunomodulatory properties},
  author={Qilin Huang and Yi Yang and Chen Luo and Y. Wen and Ruo-hong Liu and Shuai Li and Tao Chen and H. Sun and L. Tang},
  journal={Stem Cell Research \& Therapy},
  year={2019},
  volume={10}
}
BackgroundPlacenta-derived MSCs (P-MSCs) represent a promising tool for cell-based therapeutic applications. However, the increasing demand for P-MSCs in clinical trials makes high quality and large number of P-MSCs mandatory. Here, we aim to develop an efficient protocol for P-MSC isolation and culture.MethodsThe modified explant culture (MEC) method by combining an initial mild enzymatic reaction with the subsequent explant culture was developed to simultaneously produce various P-MSCs from… Expand
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