An efficient prebiotic synthesis of cytosine and uracil

@article{Robertson1995AnEP,
  title={An efficient prebiotic synthesis of cytosine and uracil},
  author={Michael P. Robertson and Stanley L. Miller},
  journal={Nature},
  year={1995},
  volume={375},
  pages={772-774}
}
IN contrast to the purines1–3, the routes that have been proposed for the prebiotic synthesis of pyrimidines from simple precursors give only low yields. Cytosine can be synthesized from cyano-acetylene and cyanate4,5; the former precursor is produced from a spark discharge in a CH4/N2 mixture4,5 and is an abundant interstellar molecule6. But this reaction requires relatively high concentrations of cyanate (>0.1 M), which are unlikely to occur in aqueous media as cyanate is hydrolysed rapidly… 
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Synthesis of pyrimidines and triazines in ice: implications for the prebiotic chemistry of nucleobases.
TLDR
The generation of both pyrimidines and triazines in comparable yields from urea, together with a possible role for triazines as alternative nucleobases, opens new perspectives on the prebiotic chemistry of informational polymers.
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