An efficient palladium-catalyzed C-H alkoxylation of unactivated methylene and methyl groups with cyclic hypervalent iodine (i(3+) ) oxidants.

@article{Shan2013AnEP,
  title={An efficient palladium-catalyzed C-H alkoxylation of unactivated methylene and methyl groups with cyclic hypervalent iodine (i(3+) ) oxidants.},
  author={G. Shan and Xinglin Yang and Yu Zong and Yu Rao},
  journal={Angewandte Chemie},
  year={2013},
  volume={52 51},
  pages={
          13606-10
        }
}
All the hype: The title reaction has been developed for the facile synthesis of a variety of complex alkyl ethers. Cyclic hypervalent iodine (I(3+) ) reagents serve as oxidants for this unique CH alkoxylation reaction. The reaction demonstrates excellent reactivity, good functional-group tolerance, and high yields. Q=8-aminoquinoline-derived auxiliary. 
82 Citations
Cobalt-catalyzed peri-selective alkoxylation of 1-naphthylamine derivatives
  • 6
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 72 REFERENCES
Palladium-catalyzed direct ethynylation of C(sp3)-H bonds in aliphatic carboxylic acid derivatives.
  • 252
  • PDF
A highly selective catalytic method for the oxidative functionalization of C-H bonds.
  • 682
Palladium-catalyzed oxygenation of unactivated sp3 C-H bonds.
  • 440
Palladium-catalyzed alkoxylation of N-methoxybenzamides via direct sp2 C-H bond activation.
  • 124
Serial ligand catalysis: a highly selective allylic C-H oxidation.
  • 260
  • PDF
Palladium-catalyzed ortho-alkoxylation of anilides via C-H activation.
  • 96
Synthesis of dibenzofurans via palladium-catalyzed phenol-directed C-H activation/C-O cyclization.
  • 237
Highly regioselective arylation of sp3 C-H bonds catalyzed by palladium acetate.
  • 839
Pd(II)-catalyzed olefination of sp3 C-H bonds.
  • 255
...
1
2
3
4
5
...