An efficient method for the determination of enantiomeric purity of racemic amino acids using micellar chromatography, a green approach.

@article{Alwera2020AnEM,
  title={An efficient method for the determination of enantiomeric purity of racemic amino acids using micellar chromatography, a green approach.},
  author={Shiv Alwera and Vijay Alwera and Suman Sehlangia},
  journal={Biomedical chromatography : BMC},
  year={2020},
  pages={
          e4943
        }
}
  • Shiv Alwera, Vijay Alwera, Suman Sehlangia
  • Published 2020
  • Chemistry, Medicine
  • Biomedical chromatography : BMC
  • A simple, sensitive and green micellar liquid chromatographic method (RP-HPLC) was developed for enantioseparation of four racemic amino acids, namely, (RS)-selenomethionine, (RS)-methionine, (RS)-cysteine and (RS)-penicillamine. The aqueous solution of sodium dodecyl sulphate and Brij-35 was prepared and used as mobile phase for HPLC analysis. Activated esters of (S)-ibuprofen, (S)-ketoprofen, and (S)-levofloxacin were synthesized by reacting them with N-hydroxybenzotriazole. These esters were… CONTINUE READING
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