An efficient green multi-component reaction strategy for the synthesis of highly functionalised pyridines and evaluation of their antibacterial activities.

Abstract

An efficient green multi-component reaction (MCR) method has been developed for the synthesis of 2-amino-4-aryl/heteroaryl-6-(pyridin-2-ylthio)pyridine-3,5-dicarbonitrile(s) via a 3-component reaction of aryl aldehyde(s), malononitrile and 2-mercaptopyridine in the presence of K2CO3 under solvent free reaction conditions (SFRC) using grinding technique at… (More)

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@article{Reddy2013AnEG, title={An efficient green multi-component reaction strategy for the synthesis of highly functionalised pyridines and evaluation of their antibacterial activities.}, author={Lakkireddy Srinivasula Reddy and Tirumalareddy Ram Reddy and Reddy Bodireddy Mohan and Avula Mahesh and Yeramanchi Lingappa and Nallagondu Chinna Gangi Reddy}, journal={Chemical & pharmaceutical bulletin}, year={2013}, volume={61 11}, pages={1114-20} }