An efficient gene-gene interaction test for genome-wide association studies in trio families


MOTIVATION Several efficient gene-gene interaction tests have been developed for unrelated case-control samples in genome-wide association studies (GWAS), making it possible to test tens of billions of interaction pairs of single-nucleotide polymorphisms (SNPs) in a reasonable timeframe. However, current family-based gene-gene interaction tests are… (More)
DOI: 10.1093/bioinformatics/btw077