An efficient detection agent for the high throughput screening of recombinant manufacturing cell lines.

Abstract

To ensure the selection of high producing recombinant cell lines, a number of screening processes were developed in the presence of detection agents. Here, CHO cell lines secreting recombinant antibodies were detected in semi-solid medium containing detection agents. The aim was to compare two protein A-derived detection agents to two commercial fluorescent… (More)
DOI: 10.1016/j.jim.2013.08.011

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