An efficient approach for glomerular filtration rate assessment in older adults.

  title={An efficient approach for glomerular filtration rate assessment in older adults.},
  author={Peter Martus and Natalie Ebert and Markus van der Giet and Olga Jakob and Elke Schaeffner},
  journal={British journal of clinical pharmacology},
  volume={78 2},
AIMS Assessment of glomerular filtration rate (GFR) is crucial because the GFR value defines the stage of chronic kidney disease and determines the adjustment of drug dosage. The aim was to investigate a new method for the accurate determination of GFR in older adults based on the combination of an exogenous filtration marker, iohexol, and an endogenous marker, serum creatinine or cystatin C. METHODS We combined variables for the estimation of GFR with a reduced set of measurements of the… 

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