An efficient approach for glomerular filtration rate assessment in older adults.

  title={An efficient approach for glomerular filtration rate assessment in older adults.},
  author={P. Martus and N. Ebert and M. van der Giet and O. Jakob and E. Schaeffner},
  journal={British journal of clinical pharmacology},
  volume={78 2},
  • P. Martus, N. Ebert, +2 authors E. Schaeffner
  • Published 2014
  • Chemistry, Medicine
  • British journal of clinical pharmacology
  • AIMS Assessment of glomerular filtration rate (GFR) is crucial because the GFR value defines the stage of chronic kidney disease and determines the adjustment of drug dosage. The aim was to investigate a new method for the accurate determination of GFR in older adults based on the combination of an exogenous filtration marker, iohexol, and an endogenous marker, serum creatinine or cystatin C. METHODS We combined variables for the estimation of GFR with a reduced set of measurements of the… CONTINUE READING
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