An efficient and general approach to beta-functionalized ketones.

@article{Jiao2007AnEA,
  title={An efficient and general approach to beta-functionalized ketones.},
  author={Jingliang Jiao and Larry X Nguyen and Dennis R Patterson and Robert A Flowers},
  journal={Organic letters},
  year={2007},
  volume={9 7},
  pages={1323-6}
}
[structure: see text]. The oxidation of selected anions (N3-, SCN-, I-, and Br-) by ceric ammonium nitrate (CAN) in the presence of substituted cyclopropyl alcohols provides a novel approach to beta-functionalized ketones. The protocol has a number of advantages including short reaction times, ease of reagent handling, and mild, neutral reaction conditions… CONTINUE READING