An efficient and exact stochastic simulation method to analyze rare events in biochemical systems

@inproceedings{Kuwaharaa2008AnEA,
  title={An efficient and exact stochastic simulation method to analyze rare events in biochemical systems},
  author={Hiroyuki Kuwaharaa and Ivan Murab},
  year={2008}
}
  • Hiroyuki Kuwaharaa, Ivan Murab
  • Published 2008
In robust biological systems, wide deviations from highly controlled normal behavior may be rare, yet they may result in catastrophic complications. While in silico analysis has gained an appreciation as a tool to offer insights into system-level properties of biological systems, analysis of such rare events provides a particularly challenging computational problem. This paper proposes an efficient stochastic simulation method to analyze rare events in biochemical systems. Our new approach can… CONTINUE READING