An early role of maternal mRNA in establishing the dorsoventral pattern in pelle mutant Drosophila embryos.

@article{MllerHoltkamp1985AnER,
  title={An early role of maternal mRNA in establishing the dorsoventral pattern in pelle mutant Drosophila embryos.},
  author={Felix M{\"u}ller-Holtkamp and Douglas C. Knipple and Eveline Seifert and Herbert Jaeckle},
  journal={Developmental biology},
  year={1985},
  volume={110 1},
  pages={238-46}
}
Mutations of the maternal effect locus pelle (pll) cause dorsalized Drosophila embryos. In extreme mutants, the embryo develops into a long hollow tube of dorsal cuticular structures with no sign of ventral pattern elements. Injection of wild-type cytoplasm or poly(A)+RNA into mutant pll embryos partially restores the normal pattern. Rescuing activity is present in the wild-type cytoplasm until the late blastoderm stage, but is already absent from the poly(A)+RNA fraction by the time of pole… CONTINUE READING