An autonomously replicating sequence for use in a wide range of budding yeasts.

@article{Liachko2014AnAR,
  title={An autonomously replicating sequence for use in a wide range of budding yeasts.},
  author={Ivan Liachko and Maitreya J. Dunham},
  journal={FEMS yeast research},
  year={2014},
  volume={14 2},
  pages={364-7}
}
The initiation of DNA replication at replication origins is essential for the duplication of genomes. In yeast, the autonomously replicating sequence (ARS) property of replication origins is necessary for the stable maintenance of episomal plasmids. However, because the sequence determinants of ARS function differ among yeast species, current ARS modules are limited for use to a subset of yeasts. Here, we describe a short ARS sequence that functions in at least 10 diverse species of budding… CONTINUE READING
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