An automatic reaction control chemical ionization technique in ion trap detector for quantitative plasma profding of arecoline in treated alzheimer patients.

Abstract

An automatic reaction control chemical ionization technique in an ion trap detector (lTD) was used to quantitate the levels of the cholinergic drug, arecoline, in plasma of treated patients with Alzheimer's disease. The chemical ionization reaction was carried out with acetonitrile. The protonated molecules of arecoline (m I z 156) and the internal standard… (More)
DOI: 10.1016/1044-0305(91)80011-U

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@article{Shetty1991AnAR, title={An automatic reaction control chemical ionization technique in ion trap detector for quantitative plasma profding of arecoline in treated alzheimer patients.}, author={H. Umesha Shetty and Eileen M. Daly and Nigel H. Greig and Stanley I. Rapoport and Timothy T. Soncrant}, journal={Journal of the American Society for Mass Spectrometry}, year={1991}, volume={2 2}, pages={168-73} }