An automated assay of the behavioral effects of cocaine injections in adult Drosophila

@article{Dimitrijevi2004AnAA,
  title={An automated assay of the behavioral effects of cocaine injections in adult Drosophila
},
  author={Nikola Dimitrijevi{\'c} and Svetlana Dzitoyeva and Hari Manev},
  journal={Journal of Neuroscience Methods},
  year={2004},
  volume={137},
  pages={181-184}
}
High Throughput Measurement of Locomotor Sensitization to Volatilized Cocaine in Drosophila melanogaster
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FlyBong is a new and improved method for inducing and measuring locomotor sensitization to cocaine in individual Drosophila, and it is validated by showing that locomot sensitization at either the population or individual level is absent in the mutants for circadian genes period, Clock, and cycle.
Genetics of Cocaine and Methamphetamine Consumption and Preference in Drosophila melanogaster
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Results suggest that variation in consumption and development of preference for both cocaine and methamphetamine is mediated, at least in part, through a neural network that comprises dopaminergic projections to the mushroom bodies.
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How Drosophila is an efficient and cost-effective model organism for identifying novel candidate genes and molecular mechanisms involved in the behavioral responses to psychostimulant drugs is discussed.
Cocaine Tolerance in Honey Bees
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The authors' data show clear short and long-term behavioural responses of bees to cocaine administration, but caution that, despite the small size of the bee brain, measures of biogenic amines conducted at the whole-brain level may not reveal neurochemical effects of the drug.
Drosophila melanogaster as a model to study drug addiction
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The advantages of using the fly to study drug-related behavior, the molecular mechanisms and neural circuits underlying drug-induced behavior in flies are described, and a brief overview of the behavioral assays used are provided.
First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians
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Demonstration of pharmacologically selective behavioral sensitization in planarians suggests that these flatworms represent a sensitive in-vivo model to study cocaine Behavioral sensitization and to screen potential abuse-deterrent therapeutics.
GABA-B receptors in Drosophila.
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