An autologously generated platelet-rich plasma suturable membrane may enhance peripheral nerve regeneration after neurorraphy in an acute injury model of sciatic nerve neurotmesis.

@article{Giannessi2014AnAG,
  title={An autologously generated platelet-rich plasma suturable membrane may enhance peripheral nerve regeneration after neurorraphy in an acute injury model of sciatic nerve neurotmesis.},
  author={Elisabetta Giannessi and Alessandra Coli and Maria Rita Stornelli and Vincenzo Miragliotta and Andrea Pirone and Carla Lenzi and Silvia Burchielli and Giovanni Vozzi and Carmelo de Maria and Margherita Giorgetti},
  journal={Journal of reconstructive microsurgery},
  year={2014},
  volume={30 9},
  pages={617-26}
}
BACKGROUND The aim of this study was to investigate the ability of suturable platelet-rich plasma (PRP) membrane to promote peripheral nerve regeneration after neurotmesis and neurorraphy. METHODS A total of 36 rats were used: 32 animals underwent surgery and were split in two groups. An interim sacrifice was performed at 6 weeks postsurgery and final sacrifice at 12 weeks; four animals did not sustain nerve injury and served as control. Clinical, electromyographic (EMG), gross, and… CONTINUE READING
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