An atlas of genetic influences on human blood metabolites

@inproceedings{Shin2014AnAO,
  title={An atlas of genetic influences on human blood metabolites},
  author={So-Youn Shin and Eric B. Fauman and Ann-Kristin Petersen and Jan Krumsiek and Rita Santos and Jie Huang and Matthias Arnold and Idil Erte and Vincenzo Forgetta and Tsun-Po Yang and Klaudia Walter and Cristina Menni and Lu Chen and Louella J. Vasquez and Ana M Valdes and Craig L. Hyde and Vicky Wang and Daniel Ziemek and Phoebe M. Roberts and Li Xi and Elin Grundberg and Melanie Waldenberger and J. Brent Richards and Robert P. Mohney and Michael V. Milburn and Sally John and Jeff K. Trimmer and Fabian Joachim Theis and John P. Overington and Karsten Suhre and Mary Julia Brosnan and Christian Gieger and Gabi Kastenm{\"u}ller and Timothy David Spector and Nicole Soranzo},
  booktitle={Nature Genetics},
  year={2014}
}
  • So-Youn Shin, Eric B. Fauman, +32 authors Nicole Soranzo
  • Published in Nature Genetics 2014
  • Medicine, Biology
  • Genome-wide association scans with high-throughput metabolic profiling provide unprecedented insights into how genetic variation influences metabolism and complex disease. Here we report the most comprehensive exploration of genetic loci influencing human metabolism thus far, comprising 7,824 adult individuals from 2 European population studies. We report genome-wide significant associations at 145 metabolic loci and their biochemical connectivity with more than 400 metabolites in human blood… CONTINUE READING

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