An astrocyte bridge from synapse to blood flow

@article{Parri2003AnAB,
  title={An astrocyte bridge from synapse to blood flow},
  author={Rheinallt Parri and V. Crunelli},
  journal={Nature Neuroscience},
  year={2003},
  volume={6},
  pages={5-6}
}
  • Rheinallt Parri, V. Crunelli
  • Published 2003
  • Biology, Medicine
  • Nature Neuroscience
  • Neural activity locally increases cerebral blood flow to deliver oxygen to working neurons. A new paper shows that astrocytes can detect activity at glutamatergic synapses via calcium changes in astrocytic endfeet and directly couple it to blood flow in vitro and in vivo. 
    76 Citations
    Astrocytes act as signal transducer in neuronal activation and cerebral arteriole vasodilation
    • 2
    Blood vessels and parkinsonism.
    • 29
    • PDF
    Molecular Mechanisms of Astrocyte Vesicle Fusion at Synaptic Interfaces
    Intercellular Signaling Pathway among Endothelia, Astrocytes and Neurons in Excitatory Neuronal Damage
    • 20
    • PDF
    Spatiotemporal Evolution of Functional Hemodynamic Changes and Their Relationship to Neuronal Activity
    • 99
    • PDF
    Extended spiking neural P systems with excitatory and inhibitory astrocytes
    • 31
    • PDF
    Rapid antidepressant effect of ketamine correlates with astroglial plasticity in the hippocampus
    • 36

    References

    SHOWING 1-10 OF 15 REFERENCES
    Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
    • 1,318
    • PDF
    Does glutamate image your thoughts?
    • 114
    • PDF
    Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.
    • L. Pellerin, P. Magistretti
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1994
    • 2,162
    • PDF
    Glia: listening and talking to the synapse
    • P. Haydon
    • Biology, Medicine
    • Nature Reviews Neuroscience
    • 2001
    • 1,337
    • PDF
    Glial calcium: homeostasis and signaling function.
    • 656
    • PDF
    EDHF: bringing the concepts together.
    • 832
    • PDF