An asthma-associated genetic variant of STAT6 predicts low burden of ascaris worm infestation

Abstract

Th-2 immune mechanisms are involved in the pathology of asthma and in the protective immune response to parasitic worms. Common upregulating genetic variants of Th-2 immune signalling are risk factors for asthma, and we tested whether they may confer a counteradvantage in protecting against parasitic worms. We examined the intensity of infection by the… (More)
DOI: 10.1038/sj.gene.6364148

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