An association of anti-elastin IgA antibodies with development of retinopathy in diabetic children.

@article{Nicoloff2000AnAO,
  title={An association of anti-elastin IgA antibodies with development of retinopathy in diabetic children.},
  author={George Nicoloff and Stephan Baydanoff and N Stanimirova and Ch Petrova and Petkama Christova},
  journal={General pharmacology},
  year={2000},
  volume={35 2},
  pages={83-7}
}
An important factor in the development of vascular wall alterations is degradation of the elastic fiber major protein-elastin. Elastin peptides derived from this degradation are present in the circulating blood and they are a stimulus for increased production of anti-elastin antibodies (AEAb). The aim of the present study was to examine the possible association between serum elastin AEAb and the development of diabetic vascular complications. Levels of AEAb (IgG, IgM and IgA) were determined by… CONTINUE READING

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